COMPACT Publications

1 - Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics Cornelia Lorenzer; Mehrdad Dirin; Anna-Maria Winkler; Volker Baumann; Johannes Winkler.
Journal of Controlled Release

2 - Carrier interactions with the biological barriers of the lung: Advanced in vitro models and challenges for pulmonary drug delivery Cristiane de Souza Carvalho ; Nicole Daum ; Claus-Michael Lehr.
Advanced Drug Delivery Reviews

3 - Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides Luís Vasconcelos ; Fatemeh Madan ; Piret Arukuusk; Ly Pärnaste; Astrid Gräslund; Ülo Langel.
Biochimica et Biophysica Acta

4 - Measurement of the Average Mass of Proteins Adsorbed to a Nanoparticle by Using a Suspended Microchannel Resonator Reza Nejadnik; Wim Jiskoot.
Wiley Online Library

5 - Dynamic responses in small intestinal mucus: Relevance for the maintenance of an intact barrier Catherine Taylor Nordgård; Kurt I. Draget.
European Journal of Pharmaceutics and Biopharmaceutics

6 - Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation Marie Boegh; María García-Díaz; Anette Müllertz; Hanne Mørck Nielsen
European Journal of Pharmaceutics and Biopharmaceutics

7 - Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro

8 - Improved insulin loading in poly(lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids María García-Díaz; Camilla Foged ;Hanne Mørck Nielsen.
International Journal of Pharmaceutics

9 - Abrasion of Adsorbed Protein is the Root Cause of Sub-Visible Particle Formation during Stirring A.S. Sediq, R.B. van Duijvenvoorde ,W. Jiskoot, M.R. Nejadnik
Journal of Pharmaceutical Sciences

10 - Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models Marius Hittinge; Jenny Juntke; Stephanie Kletting; Nicole Schneider-Daum; Cristiane de Souza Carvalho; Claus-Michael Lehr
Advanced Drug Delivery Reviews

11 - Overcoming the pulmonary barrier: new insights to improve the efficiency of inhaled therapeutics Xabier Murgia ; Cristiane De Souza Carvalho; Claus-Michael Lehr
European Journal of Nanomedicine

12 - Overview of Inhaled Nanopharmaceuticals Claus-Michael Lehr; Sarah Barthold; Nicole Kunschke ;Xabier Murgia ;Brigitta Loretz; Cristiane De Souza Carvalho ; Claus-Michael Lehr
ISAM Textbook of Aerosol Medicine, Chapter: 8.1

13 - IgG-loaded hyaluronan-based dissolving microneedles for intradermal protein delivery W. Wim Jiskoot; Joke Bouwstra; Juha Mönkäre; M. Reza Nejadnik; Khalil Baccouche; Stefan Romeijn
Journal of Controlled Release

14 - Conjugation of Cell-Penetrating Peptides to Parathyroid Hormone Affects Its Structure, Potency, and Transepithelial Permeation Mie Kristensen; Anne Marit de Groot ; Jens Berthelsen ; Henrik Franzyk; Alice Sijts; Hanne Mørck Nielsen
Bioconjugate Chemistry

15 - Liposome functionalization with copper-free “click chemistry” Erik Oude Blenkea; Gruson Klaasseb; Hannes Mertenc; Andreas Plückthunc; Enrico Mastrobattistaa; Nathaniel I. Martinb
Journal of Controlled Release

16 - Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond) Ulrich Lächelt; Ernst Wagner
Chemical Reviews

17 - Complexity in the therapeutic delivery of RNAi medicines: an analytical challenge Camilla Foged, Stefano Colombo, Xianghui Zeng, Heloise Ragelle
Expert Opinion

18 - Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles Colombo, S.,Cun, D.,Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, B., Yaghmur, A.,Braeckmans, K., Nielsen, H.M. ,Foged, C
J. Control. Release 201, 22-31

19 - A convergent uptake route for peptide- and polymer-based nucleotide delivery systems Lindberg, Staffan; Regberg, Jakob; Eriksson, Jonas; Helmfors, Henrik; Munoz-Alarcon, Andres; Srimanee, Artita; Figueroa, Ricardo A.; Hallberg, Einar; Ezzat, Kariem; Lange, Ulo
J. Control. Release - MAY 28 2015

20 - Peptide-Based Delivery of Oligonucleotides Across Blood-Brain Barrier Model Srimanee, Artita; Regberg, Jakob; Hallbrink, Mattias; Kurrikoff, Kaido; Veiman, Kadi-Liis; Vajragupta, Opa; Langel, Ulo
International journal of peptide research and therapeutics

21 - Rational design of a series of novel amphipathic cell-penetrating peptides Regberg, Jakob; Srimanee, Artita; Erlandsson, Mikael; Sillard, Rannar; Dobchev, Dimitar A.; Karelson, Mati; Langel, Ulo
International Journal of Pharmaceutics

22 - Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems Wouter P.R. Verdurmen, Manuel Luginbühl, Annemarie Honegger, Andreas Plückthun
J. Control. Release

23 - Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adverse effects in vitroXianghui Zeng, Anne Marit de Groot, Alice J.A.M. Sijts, Femke Broere, Erik Oude Blenke, Stefano Colombo, Willem van Eden, Henrik Franzyk, Hanne Mørck, Camilla Foged
Royal society of Chemistry

24 - IgG-loaded hyaluronan-based dissolving microneedles for intradermal protein delivery Juha Mönkäre, M. Reza Nejadnik, Khalil Baccouche, Stefan Romeijn, Wim Jiskoot, Joke A. Bouwstra
Journal of Controlled Release

25 - "Targeted siRNA Delivery Using a Cationic Lipo-Oligoaminoamide Core and a Transferrin Protein and Influenza Peptide Shell (Not directly funded by COMPACT)Ernst Wagner; Wei Zhang; Katharina Müller; Eva Kessel; Sören Reinhard; Dongsheng He; Philipp M. Klein Miriam Höhn; Wolfgang Rödl
Advanced Healthcare Materials 2016

26 - Coiled coil interactions for the targeting of liposomes for nucleic acid delivery Erik OudeErik Oude Blenke; Joep van den Dikkenberg; Bartjan van Kolck; Alexander Kros; Enrico Mastrobattista
Royal Society of Chemistry

27 - pH-responsive PepFect cell-penetrating peptidesJakob Regberg; ; Luis Vasconcelos; Fatemeh Madani; Ülo Langel; Mattias Hällbrink

28 - Role of scavenger receptors in peptide-based delivery of plasmid DNA across a blood–brain barrier modelArtita Srimaneea, Jakob Regbergb, Mattias Hällbrinkb, Opa Vajraguptad, Ülo Langel
International Journal of Pharmaceutics

29 - Determination of the activity of maleimide-functionalized phospholipids during preparation of liposomesMira Oswald, Simon Geissler, Achim Goepferich
International Journal of Pharmaceutics

30 - How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino AmidesSören Reinhard, Ernst Wagner
Macromolecular Bioscience 2016

31 - Preparation of nanosized coacervates of positive and negative starch derivatives intended for pulmonary delivery of proteinsBrigitta Loretz; Sarah Barthold; Stephanie Kletting ; Julian Taffner; Cristiane de Souza Carvalho-Wodarz; Elise Lepeltier; Brigitta Loretz; Claus-Michael Lehr
Journal of Materials Chemistry

32 - Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier Stephanie Kletting ; Cristiane de Souza Carvalho-Wodarz Urska Repnik,; Gareth Griffiths; Ulrike Fischer; Eckart Meese; Hanno Huwer; Dagmar Wirth; Tobias May ; Nicole Schneider-Daum; Claus-Michael Lehr
ALTEX 2016